Dual-mode model predictive control of an omnidirectional wheeled inverted pendulum

This article describes the position and heading control of a novel form of omnidirectional wheeled inverted pendulum platform known as a Collinear Mecanum Drive. This concept uses four collinear Mecanum wheels to balance in a similar manner to a typical two-wheeled inverted pendulum, whilst also being able to simultaneously translate directly along its balance axis. Control is performed using a constrained time-optimal infinite horizon model predictive controller, with feasibility maintained across the full reference input set. Explored in this article is the derivation of the system dynamics model and controller, a systematic approach to selection of controller parameters and analysis of their effect on control performance and complexity, and an evaluation of the controller's efficacy in both simulation and on a real-world experimental prototype for simple and complex trajectories

Velocity constrained trajectory generation for a collinear Mecanum wheeled robot

While much research has been conducted into the generation of smooth trajectories for underactuated unstable aerial vehicles such as quadrotors, less attention has been paid to the application of the same techniques to ground based omnidirectional dynamically balancing robots. These systems have more control authority over their linear accelerations than aerial vehicles, meaning trajectory smoothness is less of a critical design parameter. However, when operating in indoor environments these systems must often adhere to relatively low velocity constraints, resulting in very conservative trajectories when enforced using existing trajectory optimisation methods. This paper makes two contributions; this gap is bridged by the extension of these existing methods to create a fast velocity constrained trajectory planner, with trajectory timing characteristics derived from the optimal minimum-time solution of a simplified acceleration and velocity constrained model. Next, a differentially flat model of an omnidirectional balancing robot utilizing a collinear Mecanum drive is derived, which is used to allow an experimental prototype of this configuration to smoothly follow these velocity constrained trajectories

Design and control of a novel omnidirectional dynamically balancing platform for remote inspection of confined and cluttered environments

Remote inspection is a long standing field of interest for robotics researchers, in which robots are used to undertake inspection tasks in environments too hazardous or inaccessible to be directly entered by a human. Recent advances in gridscale battery storage have created a new set of unique hazardous indoor spaces with characteristics unsuitable for the deployment of existing teleoperated inspection robots. This paper outlines the problems encountered in these new environments, analyses existing approaches to robotic platform design, and proposes a better suited novel platform design, based on a dynamically balancing arrangement of Mecanum wheels. Its inverse kinematic and dynamics models are developed, a proof of concept prototype is constructed, and a constrained predictive controller is derived from the developed model. Experimental results demonstrate the efficacy of this new concept

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

Background: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19. Methods: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from across the UK. Eligible and consenting patients were randomly assigned (1:1) to receive either usual care alone (usual care group) or usual care plus high-titre convalescent plasma (convalescent plasma group). The primary outcome was 28-day mortality, analysed on an intention-to-treat basis. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936. Findings: Between May 28, 2020, and Jan 15, 2021, 11558 (71%) of 16287 patients enrolled in RECOVERY were eligible to receive convalescent plasma and were assigned to either the convalescent plasma group or the usual care group. There was no significant difference in 28-day mortality between the two groups: 1399 (24%) of 5795 patients in the convalescent plasma group and 1408 (24%) of 5763 patients in the usual care group died within 28 days (rate ratio 1·00, 95% CI 0·93–1·07; p=0·95). The 28-day mortality rate ratio was similar in all prespecified subgroups of patients, including in those patients without detectable SARS-CoV-2 antibodies at randomisation. Allocation to convalescent plasma had no significant effect on the proportion of patients discharged from hospital within 28 days (3832 [66%] patients in the convalescent plasma group vs 3822 [66%] patients in the usual care group; rate ratio 0·99, 95% CI 0·94–1·03; p=0·57). Among those not on invasive mechanical ventilation at randomisation, there was no significant difference in the proportion of patients meeting the composite endpoint of progression to invasive mechanical ventilation or death (1568 [29%] of 5493 patients in the convalescent plasma group vs 1568 [29%] of 5448 patients in the usual care group; rate ratio 0·99, 95% CI 0·93–1·05; p=0·79). Interpretation: In patients hospitalised with COVID-19, high-titre convalescent plasma did not improve survival or other prespecified clinical outcomes. Funding: UK Research and Innovation (Medical Research Council) and National Institute of Health Research